HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25609649
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045893 - positive regulation of DNA-templated transcription and 1 others more... GO:0051726 - regulation of cell cycle
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 334
+	Hs
		209378 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05
+	Hs
		402410 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	Hs
		556832 CREB1_HUMAN (54-307): 2.89e-29: 116: 14.84		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		569504 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		402100 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71
+	Hs
		402538 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54
+	Hs
		402320 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15
+	Hs
		402335 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29
+	Hs
		196941 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39
+	Hs
		209390 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05
+	Hs
		570017 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	Dm
		576069 JRA_DROME (7-324): 1.23e-26: 108: 23.59		EBI_DROME (6-202): 3.98e-57: 198: 27.75
+	Hs
		570041 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		TBL1R_HUMAN (82-333): 6.52e-60: 201: 26.28
+	Mm
		1257400 CR3L1_MOUSE (121-303): 3.68e-23: 101: 17.94		FBXW7_MOUSE (198-333): 2.14e-28: 117: 30.15
+	Hs
		1281297 CR3L1_HUMAN (121-303): 5.84e-22: 98.2: 17.94		FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15
+	Hs
		569952 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29
+	Hs
		196953 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39