HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: NF2L2 (Q16236)
Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nrf-2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2)
Gene: NFE2L2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.930

The method score is based on:

Property Details
Experiments 20194533, 32911434, 9872330, 20232342, 19666106
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, pull down, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_1~bZIP_Maf
Common GO terms GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 11 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 331
Hs

1 605
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024