HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: RHG22 (Q7Z5H3)
Rho GTPase-activating protein 22 (Rho-type GTPase-activating protein 22)
Gene: ARHGAP22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005096 - GTPase activator activity GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 698
+	Hs
		568098 JUND_HUMAN (5-331): 5.93e-47: 163: 45.86		RHG22_HUMAN (1-698): 0: 587: 100.00
+	Hs
		547824 ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33		RHG22_HUMAN (1-698): 0: 587: 100.00
+	Hs
		556906 CREB1_HUMAN (54-307): 2.89e-29: 116: 14.84		RHG22_HUMAN (1-698): 0: 587: 100.00
+	Hs
		579148 ATF1_HUMAN (42-306): 1.3e-26: 107: 13.97		RHG22_HUMAN (1-698): 0: 587: 100.00
+	Hs
		401465 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		P85A_HUMAN (101-649): 2.79e-75: 258: 14.26
+	Hs
		402666 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		3BP1_HUMAN (162-319): 3.15e-20: 97.4: 38.10
+	Hs
		569591 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		RHG04_HUMAN (173-354): 4.9e-19: 94: 36.84