HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36629882, 25609649
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 780
+	Hs
		401966 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		556937 CREB1_HUMAN (54-307): 2.89e-29: 116: 14.84		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		547795 ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Mm
		1141395 NF2L2_MOUSE (10-314): 8.57e-29: 118: 15.48		CUL3_MOUSE (8-780): 0: 754: 22.96
+	Hs
		1041044 CR3L3_HUMAN (70-314): 2.55e-29: 118: 15.59		CUL1_HUMAN (11-780): 0: 748: 27.84