Interactor 1: RPC4 (P05423)
DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D) (Protein BN51) (RNA polymerase III 47 kDa subunit) (RPC53 homolog)
Gene: POLR3D

Interactor 2: RPC2 (Q9NW08)
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)
Gene: POLR3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 26186194, 28514442, 24981860, 33961781, 12391170, 35271311, 33674783
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb2_4~RNA_pol_Rpc4
Common GO terms GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
GO:0005829 - cytosol
GO:0032728 - positive regulation of interferon-beta production
and 3 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 398
Hs

1 1133
+ Hs
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024