HitPredict

Interactor 1: RPC4 (P05423)
DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D) (Protein BN51) (RNA polymerase III 47 kDa subunit) (RPC53 homolog)
Gene: POLR3D

Interactor 2: RPC10 (Q9Y2Y1)
DNA-directed RNA polymerase III subunit RPC10 (RNA polymerase III subunit C10) (DNA-directed RNA polymerase III subunit K) (RNA polymerase III 12.5 kDa subunit) (RPC12.5) (RNA polymerase III subunit C11) (HsC11p) (RPC11) (hRPC11)
Gene: POLR3K

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	26186194, 28514442, 24981860, 12391170, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005666 - RNA polymerase III complex GO:0005829 - cytosol GO:0045087 - innate immune response GO:0051607 - defense response to virus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 398 Hs			1 108
+	Hs
		402719 RPC4_HUMAN (1-398): 1.33e-161: 461: 100.00		RPB9_HUMAN (2-108): 1.17e-36: 122: 26.79
+	Hs
		402759 RPC4_HUMAN (1-398): 1.33e-161: 461: 100.00		RPA12_HUMAN (2-108): 2.44e-22: 86: 24.55
+	Sc
		631684 RPC4_YEAST (38-389): 3.78e-81: 256: 19.24		RPC10_YEAST (1-108): 3.54e-31: 107: 50.44