HitPredict

Interactor 1: RPC4 (P05423)
DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D) (Protein BN51) (RNA polymerase III 47 kDa subunit) (RPC53 homolog)
Gene: POLR3D

Interactor 2: RPC8 (Q9Y535)
DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III subunit H) (RNA polymerase III subunit 22.9 kDa subunit) (RPC22.9)
Gene: POLR3H

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.746

Property	Details
Experiments	33961781, 35271311, 17643375, 26186194, 28514442, 24981860, 12391170
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0005666 - RNA polymerase III complex GO:0005829 - cytosol GO:0045087 - innate immune response and 1 others more... GO:0051607 - defense response to virus
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 398 Hs			1 204
+	Hs
		402726 RPC4_HUMAN (1-398): 1.33e-161: 461: 100.00		RPB7_HUMAN (1-199): 5.25e-63: 194: 17.59
+	Sc
		631660 RPC4_YEAST (38-389): 3.78e-81: 256: 19.24		RPC8_YEAST (1-202): 1.09e-72: 220: 42.79