HitPredict

Interactor 1: LA (P05455)
Lupus La protein (La autoantigen) (La ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B)
Gene: SSB

Interactor 2: IF4B (P23588)
Eukaryotic translation initiation factor 4B (eIF-4B)
Gene: EIF4B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 408 Hs			1 611
+	Hs
		403212 LA_HUMAN (1-408): 4.97e-104: 315: 100.00		PABP4_HUMAN (49-389): 1.92e-21: 100: 9.72
+	At
		285478 LRP6B_ARATH (12-258): 6.05e-55: 191: 19.48		PABP8_ARATH (5-400): 9.75e-41: 159: 10.15
+	Zm
		8143 A0A1D6ELH4_MAIZE (32-322): 1.15e-44: 165: 13.81		A0A1D6ELH4_MAIZE (94-497): 7.01e-41: 159: 10.76
+	At
		285476 LRP6B_ARATH (12-258): 6.05e-55: 191: 19.48		PABP2_ARATH (49-407): 3.4e-21: 100: 11.96
+	Mm
		665745 TIA1_MOUSE (106-327): 7.74e-43: 156: 14.16		PABP1_MOUSE (49-537): 6.94e-25: 111: 10.22
+	Hs
		1047867 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		CIRBP_HUMAN (98-257): 1.65e-29: 116: 24.85
+	Hs
		1116442 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		MSI2H_HUMAN (82-179): 1.19e-27: 115: 18.37
+	Hs
		474021 PAB4L_HUMAN (69-333): 1.17e-44: 160: 15.30		PABP4_HUMAN (49-389): 1.92e-21: 100: 9.72
+	Hs
		516541 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22
+	At
		790116 LRP6C_ARATH (11-202): 1.42e-42: 156: 20.59		PABP2_ARATH (49-407): 3.4e-21: 100: 11.96
+	Hs
		1116304 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		PAP1L_HUMAN (49-389): 3.99e-23: 105: 10.28
+	Hs
		1116542 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		PABP3_HUMAN (54-547): 1.45e-22: 104: 11.07
+	Hs
		1031352 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		PABP4_HUMAN (49-389): 1.92e-21: 100: 9.72
+	Hs
		958197 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		RBM3_HUMAN (98-241): 2.31e-22: 95.7: 24.83
+	Sc
		376709 LHP1_YEAST (8-207): 1.39e-36: 136: 21.76		PABP_YEAST (7-185): 1.17e-23: 107: 16.58
+	Hs
		516689 PABP3_HUMAN (102-408): 3.51e-32: 130: 14.02		PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22
+	Sc
		376562 PABP_YEAST (101-315): 1.22e-30: 125: 15.53		PABP_YEAST (7-185): 1.17e-23: 107: 16.58
+	Hs
		474034 PABP5_HUMAN (98-321): 2.76e-25: 108: 15.42		PAB4L_HUMAN (6-198): 1.72e-27: 116: 13.40
+	Hs
		516635 PABP5_HUMAN (98-321): 2.76e-25: 108: 15.42		PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22
+	Sc
		376663 PABP_YEAST (101-315): 1.22e-30: 125: 15.53		NSR1_YEAST (84-187): 1.96e-10: 65.3: 20.00