HitPredict

Interactor 1: LA (P05455)
Lupus La protein (La autoantigen) (La ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B)
Gene: SSB

Interactor 2: ZCRB1 (Q8TBF4)
Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 small nuclear ribonucleoprotein 31 kDa protein) (U11/U12 snRNP 31 kDa protein) (U11/U12-31K)
Gene: ZCRB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 408 Hs			1 217
+	Hs
		403212 LA_HUMAN (1-408): 4.97e-104: 315: 100.00		PABP4_HUMAN (11-196): 1.86e-23: 99.6: 12.37
+	At
		285476 LRP6B_ARATH (12-258): 6.05e-55: 191: 19.48		PABP2_ARATH (2-192): 1.12e-46: 164: 21.36
+	At
		285478 LRP6B_ARATH (12-258): 6.05e-55: 191: 19.48		PABP8_ARATH (3-195): 8.55e-45: 159: 16.83
+	Hs
		1116403 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		ZCRB1_HUMAN (1-217): 1.57e-56: 180: 100.00
+	At
		790116 LRP6C_ARATH (11-202): 1.42e-42: 156: 20.59		PABP2_ARATH (2-192): 1.12e-46: 164: 21.36
+	Hs
		1116542 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		PABP3_HUMAN (3-181): 3.06e-45: 160: 18.65
+	Hs
		474034 PAB4L_HUMAN (69-333): 1.17e-44: 160: 15.30		PABP5_HUMAN (1-179): 2.36e-39: 140: 15.54
+	Hs
		1084289 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		SRSF7_HUMAN (9-120): 7.54e-35: 125: 32.17
+	Zm
		8143 A0A1D6ELH4_MAIZE (32-322): 1.15e-44: 165: 13.81		A0A1D6ELH4_MAIZE (4-99): 1.27e-22: 96.9: 17.71
+	Hs
		474021 PAB4L_HUMAN (69-333): 1.17e-44: 160: 15.30		PABP4_HUMAN (11-196): 1.86e-23: 99.6: 12.37
+	Hs
		1047867 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		CIRBP_HUMAN (5-86): 4.16e-30: 111: 32.93
+	Hs
		1116304 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		PAP1L_HUMAN (11-145): 2.3e-26: 107: 17.78
+	Mm
		665745 TIA1_MOUSE (106-327): 7.74e-43: 156: 14.16		PABP1_MOUSE (11-99): 1.5e-22: 96.9: 19.10
+	Hs
		1031352 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		PABP4_HUMAN (11-196): 1.86e-23: 99.6: 12.37
+	Hs
		516541 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		PABP1_HUMAN (11-99): 1.42e-22: 96.9: 19.10
+	Hs
		958197 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		RBM3_HUMAN (5-91): 1.58e-24: 96.3: 29.89
+	Sc
		376709 LHP1_YEAST (8-207): 1.39e-36: 136: 21.76		PABP_YEAST (11-208): 3.81e-23: 98.5: 15.60
+	Hs
		516689 PABP3_HUMAN (102-408): 3.51e-32: 130: 14.02		PABP1_HUMAN (11-99): 1.42e-22: 96.9: 19.10
+	Sc
		376562 PABP_YEAST (101-315): 1.22e-30: 125: 15.53		PABP_YEAST (11-208): 3.81e-23: 98.5: 15.60
+	Hs
		1073582 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		SF3B4_HUMAN (101-215): 5.02e-12: 66.1: 9.84