HitPredict

Interactor 1: SRC (P05480)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: EGFR (Q01279)
Epidermal growth factor receptor (EC 2.7.10.1)
Gene: EGFR

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 11274221
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1
Common GO terms GO:0004713 - protein tyrosine kinase activity
GO:0005102 - signaling receptor binding
GO:0005178 - integrin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 18 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 535
Mm

1 1210
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024