Interactor 1: SRC (P05480)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 28671696
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SAM_1, SH2~SH3_2, Ank_2~SH3_1, SH3_1~SH3_2
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007611 - learning or memory
GO:0044877 - protein-containing complex binding
GO:0097110 - scaffold protein binding
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 535
Mm

1 1730
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Last updated: 15 Jul 2024