HitPredict

Interactor 1: SRC (P05480)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: PAXI (Q8VI36)
Paxillin
Gene: Pxn

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 14636584, 16478788
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005178 - integrin binding
GO:0005856 - cytoskeleton
GO:0005925 - focal adhesion
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0007229 - integrin-mediated signaling pathway
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 535
Mm

1 591
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024