HitPredict

Interactor 1: SRC (P05480)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: SRCN1 (Q9QWI6)
SRC kinase signaling inhibitor 1 (SNAP-25-interacting protein) (SNIP) (p130Cas-associated protein) (p140Cap)
Gene: Srcin1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19146815
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0019901 - protein kinase binding GO:0019904 - protein domain specific binding GO:0034446 - substrate adhesion-dependent cell spreading GO:0043025 - neuronal cell body and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 535 Mm			1 1250
+	Mm
		763409 FYN_MOUSE (1-535): 0: 594: 68.52		SRCN1_MOUSE (1-1250): 0: 1806: 100.00
+	Mm
		639461 LYN_MOUSE (1-530): 0: 533: 52.35		SRCN1_MOUSE (1-1250): 0: 1806: 100.00
+	Hs
		523139 SRC_HUMAN (1-535): 0: 645: 98.69		SRCN1_HUMAN (36-1250): 0: 1612: 89.32
+	Hs
		337555 ABL1_HUMAN (50-535): 1.03e-171: 516: 40.16		SRCN1_HUMAN (36-1250): 0: 1612: 89.32
+	Hs
		782824 CSK_HUMAN (83-524): 2.29e-171: 493: 39.38		SRCN1_HUMAN (36-1250): 0: 1612: 89.32
+	Hs
		411754 LCK_HUMAN (27-533): 0: 559: 54.01		SKT_HUMAN (32-1158): 0: 1000: 35.83
+	Hs
		433813 LYN_HUMAN (1-530): 0: 534: 52.92		SKT_HUMAN (32-1158): 0: 1000: 35.83
+	Hs
		1046409 PTK6_HUMAN (78-528): 3.58e-156: 455: 43.20		SKT_HUMAN (32-1158): 0: 1000: 35.83