Interactor 1: KIT (P05532)
Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)
Gene: KIT

Interactor 2: SCF (P20826)
Kit ligand (Hematopoietic growth factor KL) (Mast cell growth factor) (MGF) (Steel factor) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)]
Gene: Kitlg

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 1698557
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SCF~ig
Common GO terms GO:0001541 - ovarian follicle development
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0007281 - germ cell development
and 8 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 979
Mm

1 273
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024