Interactor 1: AP2A (P05549)
Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)
Gene: TFAP2A

Interactor 2: XRCC6 (P12956)
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Gene: XRCC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 19906305
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000976 - transcription cis-regulatory region binding
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0045892 - negative regulation of DNA-templated transcription
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 437
Hs

1 609
+ Hs
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024