Interactor 1: AP2A (P05549)
Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)
Gene: TFAP2A

Interactor 2: ERBB4 (Q15303)
Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]
Gene: ERBB4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 20943952
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000976 - transcription cis-regulatory region binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008285 - negative regulation of cell population proliferation
GO:0043066 - negative regulation of apoptotic process
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 437
Hs

1 1308
+ Hs
+ Hs

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Last updated: 15 Jul 2024