HitPredict

Interactor 1: AP2A (P05549)
Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)
Gene: TFAP2A

Interactor 2: KCTD1 (Q719H9)
BTB/POZ domain-containing protein KCTD1 (Potassium channel tetramerization domain-containing protein 1)
Gene: KCTD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	33000225, 19115315
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 257
+	Hs
		403682 AP2A_HUMAN (1-437): 0: 685: 100.00		KCD15_HUMAN (1-257): 2.18e-101: 298: 79.77
+	Dr
		1150090 Q6NYI3_DANRE (16-437): 0: 613: 85.82		KCD15_DANRE (1-257): 2.26e-100: 294: 78.60
+	Hs
		1174577 AP2B_HUMAN (1-437): 0: 559: 70.96		KCTD1_HUMAN (1-257): 6.91e-99: 290: 100.00
+	Hs
		1174578 AP2C_HUMAN (1-437): 0: 557: 62.66		KCTD1_HUMAN (1-257): 6.91e-99: 290: 100.00
+	Dm
		89871 O96378_DROME (62-434): 5.33e-136: 400: 47.94		TIWAZ_DROME (15-239): 4.98e-57: 188: 49.20