HitPredict

Interactor 1: AP2A (P05549)
Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)
Gene: TFAP2A

Interactor 2: AP2B (Q92481)
Transcription factor AP-2-beta (AP2-beta) (Activating enhancer-binding protein 2-beta)
Gene: TFAP2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 18843039, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 18 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 437
Hs

1 460
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Ce
+ Ce

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Last updated: 15 Jul 2024