Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Interactor 2: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 35384245, 15289498
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Integrin_beta~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0030335 - positive regulation of cell migration
GO:0043235 - receptor complex
GO:0044877 - protein-containing complex binding
and 1 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 798
Hs

1 1367
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024