HitPredict

Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Interactor 2: FBX2 (Q9UK22)
F-box only protein 2
Gene: FBXO2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.689

Property	Details
Experiments	12140560, 33961781, 16275327, 17116465
Identification Methods	affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0043197 - dendritic spine
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 798 Hs			1 296
+	Hs
		403976 ITB1_HUMAN (1-798): 0: 794: 100.00		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		574583 ITB5_HUMAN (19-792): 0: 660: 42.64		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		574580 ITB5_HUMAN (19-792): 0: 660: 42.64		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		1350098 TEN3_HUMAN (520-739): 8e-38: 155: 19.33		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1256715 SNED1_HUMAN (510-744): 5.08e-22: 104: 14.29		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		980571 NOTC2_HUMAN (297-590): 7.37e-11: 68.2: 12.26		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		804367 NOTC1_HUMAN (514-747): 1.07e-10: 67.8: 16.80		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		624336 TENA_HUMAN (336-474): 5.37e-16: 85.2: 9.79		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		1154503 TEN4_HUMAN (356-480): 1.24e-09: 64.4: 9.22		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81