HitPredict

Interactor 1: RS31 (P05759)
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S31) (CEP76) (S37) (YS24)]
Gene: RPS31

Interactor 2: TOM1 (Q03280)
E3 ubiquitin-protein ligase TOM1 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase TOM1) (Suppressor of snRNA protein 2) (Temperature-dependent organization in mitotic nucleus protein 1)
Gene: TOM1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27552055
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HECT~ubiquitin, UBM~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Sc			1 3268
+	Sc
		477647 RL40A_YEAST (1-76): 1.13e-42: 139: 100.00		TOM1_YEAST (1-3268): 0: 4484: 100.00
+	Sc
		477424 UBI4P_YEAST (1-76): 1.31e-32: 120: 100.00		TOM1_YEAST (1-3268): 0: 4484: 100.00
+	Hs
		125347 RS27A_HUMAN (1-151): 1.46e-67: 203: 82.78		WWP2_HUMAN (2727-3266): 0: 591: 30.66
+	Hs
		924156 RS27A_HUMAN (1-151): 1.46e-67: 203: 82.78		WWP1_HUMAN (2754-3266): 0: 590: 32.82
+	Mm
		477022 UBC_MOUSE (1-135): 9.67e-34: 126: 57.78		UBE3B_MOUSE (2494-3268): 0: 638: 19.26
+	Sp
		145417 RS27B_SCHPO (1-152): 7.75e-54: 168: 86.18		PUB3_SCHPO (2686-3266): 0: 593: 32.43
+	Sc
		408371 RS31_YEAST (1-152): 3.66e-57: 177: 100.00		RSP5_YEAST (2787-3266): 0: 583: 35.79
+	Sp
		145416 RS27A_SCHPO (1-151): 3.91e-53: 166: 86.09		PUB3_SCHPO (2686-3266): 0: 593: 32.43
+	Hs
		475078 UBB_HUMAN (1-76): 4.1e-32: 115: 96.05		UBE3B_HUMAN (2494-3268): 0: 633: 19.26
+	Rn
		1140970 UBC_RAT (1-135): 9.19e-34: 126: 57.78		Q5YB86_RAT (2727-3266): 0: 606: 32.01
+	Sp
		145418 RL402_SCHPO (1-76): 2.96e-42: 138: 100.00		PUB3_SCHPO (2686-3266): 0: 593: 32.43
+	Hs
		474953 UBB_HUMAN (1-76): 4.1e-32: 115: 96.05		NEDD4_HUMAN (2658-3266): 0: 608: 30.97
+	Hs
		125112 UBB_HUMAN (1-76): 4.1e-32: 115: 96.05		WWP2_HUMAN (2727-3266): 0: 591: 30.66
+	Sc
		477293 UBI4P_YEAST (1-76): 1.31e-32: 120: 100.00		RSP5_YEAST (2787-3266): 0: 583: 35.79
+	Sp
		143368 UBI4P_SCHPO (1-76): 1.14e-32: 120: 100.00		PTR1_SCHPO (1498-2073): 3.55e-164: 575: 24.30
+	Sc
		477380 UBI4P_YEAST (1-76): 1.31e-32: 120: 100.00		HUL5_YEAST (2509-3268): 1.55e-159: 522: 20.74
+	Dm
		89880 RL40_DROME (1-76): 8.42e-35: 119: 96.05		D5SHR3_DROME (2862-3267): 4.74e-159: 502: 35.52
+	Dm
		1376481 Q9W418_DROME (1-77): 2.23e-30: 116: 94.81		Q9W325_DROME (2862-3267): 5.09e-159: 502: 35.52
+	Mm
		924239 RS27A_MOUSE (1-151): 5.26e-67: 202: 82.12		HUWE1_MOUSE (2250-2515): 3.34e-55: 217: 18.67
+	Mm
		476858 UBC_MOUSE (1-135): 9.67e-34: 126: 57.78		HUWE1_MOUSE (2250-2515): 3.34e-55: 217: 18.67