HitPredict

Interactor 1: KPCB (P05771)
Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)
Gene: PRKCB

Interactor 2: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005813 - centrosome GO:0042393 - histone binding GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 671 Hs			1 143
+	Hs
		408665 KPCB_HUMAN (1-671): 0: 774: 100.00		H2A1J_HUMAN (1-128): 1.45e-66: 199: 92.19
+	Hs
		408656 KPCB_HUMAN (1-671): 0: 774: 100.00		H2A1C_HUMAN (1-129): 5.04e-66: 198: 92.25
+	Hs
		408661 KPCB_HUMAN (1-671): 0: 774: 100.00		H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19
+	Hs
		391498 KPCB_HUMAN (1-671): 0: 774: 100.00		H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70
+	Hs
		408533 KPCB_HUMAN (1-671): 0: 774: 100.00		H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47
+	Hs
		408553 KPCB_HUMAN (1-671): 0: 774: 100.00		H2A1D_HUMAN (1-129): 1.02e-65: 197: 90.70
+	Hs
		408631 KPCB_HUMAN (1-671): 0: 774: 100.00		H2A2A_HUMAN (1-129): 7e-66: 197: 91.47
+	Hs
		408639 KPCB_HUMAN (1-671): 0: 774: 100.00		H2A3_HUMAN (1-129): 5.88e-66: 197: 91.47
+	Hs
		408623 KPCB_HUMAN (1-671): 0: 774: 100.00		H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70
+	Hs
		408674 KPCB_HUMAN (1-671): 0: 774: 100.00		H2AJ_HUMAN (1-125): 5.62e-65: 195: 93.60