HitPredict

Interactor 1: KPCB (P05771)
Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)
Gene: PRKCB

Interactor 2: KPCA (P17252)
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene: PRKCA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.871

The method score is based on:

Property Details
Experiments 32707033, 28514442, 33961781
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~C2, C1_1~Pkinase, C2~C2, Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0004697 - diacylglycerol-dependent serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 11 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 671
Hs

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Last updated: 15 Jul 2024