HitPredict

Interactor 1: KPCB (P05771)
Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)
Gene: PRKCB

Interactor 2: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	11901153, 8034666
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 671 Hs			1 586
+	Hs
		566280 KPCA_HUMAN (1-668): 0: 742: 78.89		LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00
+	Hs
		359636 KPCA_HUMAN (1-668): 0: 742: 78.89		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Mm
		554876 KPCE_MOUSE (5-662): 0: 624: 45.02		LMNA_MOUSE (3-580): 4.36e-63: 221: 53.37
+	Hs
		397132 KPCG_HUMAN (1-668): 0: 678: 66.96		GFAP_HUMAN (6-418): 1.55e-27: 117: 29.23
+	Mm
		554866 KPCE_MOUSE (5-662): 0: 624: 45.02		DESM_MOUSE (28-390): 6.47e-33: 133: 30.85
+	Mm
		554861 KPCE_MOUSE (5-662): 0: 624: 45.02		VIME_MOUSE (28-390): 1.46e-29: 123: 28.38
+	Mm
		682101 AKT1_MOUSE (239-665): 1.05e-159: 470: 37.33		LMNA_MOUSE (3-580): 4.36e-63: 221: 53.37
+	Hs
		681844 AKT1_HUMAN (239-665): 2.36e-159: 469: 37.33		K1H2_HUMAN (75-388): 3.56e-46: 170: 21.59
+	Hs
		1055200 AKT3_HUMAN (284-665): 4.8e-158: 465: 41.48		K1H2_HUMAN (75-388): 3.56e-46: 170: 21.59
+	Hs
		443354 AKT1_HUMAN (239-665): 2.36e-159: 469: 37.33		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		443355 AKT2_HUMAN (237-665): 2.34e-159: 469: 37.87		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		535333 AKT1_HUMAN (239-665): 2.36e-159: 469: 37.33		GFAP_HUMAN (6-418): 1.55e-27: 117: 29.23
+	Mm
		589625 KPCZ_MOUSE (10-86): 5.5e-12: 70.9: 36.36		VIME_MOUSE (28-390): 1.46e-29: 123: 28.38