HitPredict

Interactor 1: KPCB (P05771)
Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)
Gene: PRKCB

Interactor 2: PDLI5 (Q96HC4)
PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein)
Gene: PDLIM5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	8940095
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005080 - protein kinase C binding GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 671 Hs			1 596
+	Rn
		934617 KPCB_RAT (1-671): 0: 772: 98.81		PDLI5_RAT (1-596): 2.63e-111: 347: 87.42
+	Hs
		969104 KPCE_HUMAN (5-662): 0: 624: 44.73		PDLI5_HUMAN (1-596): 5.35e-119: 367: 100.00
+	Mm
		554924 KPCE_MOUSE (5-662): 0: 624: 45.02		PDLI5_MOUSE (1-596): 2.12e-113: 352: 87.42
+	Rn
		448415 KPCE_RAT (5-662): 0: 619: 44.73		PDLI5_RAT (1-596): 2.63e-111: 347: 87.42
+	Hs
		566498 KPCA_HUMAN (1-668): 0: 742: 78.89		TES_HUMAN (278-593): 3.29e-62: 213: 18.29
+	Hs
		408685 KPCB_HUMAN (1-671): 0: 774: 100.00		PDLI7_HUMAN (475-594): 1.12e-28: 121: 28.33
+	Mm
		934638 KPCB_MOUSE (1-671): 0: 772: 98.81		LDB3_MOUSE (3-429): 1.27e-25: 113: 27.27
+	Mm
		593492 KPCA_MOUSE (1-668): 0: 735: 78.14		LDB3_MOUSE (3-429): 1.27e-25: 113: 27.27
+	Mm
		930579 KPCG_MOUSE (17-668): 0: 673: 67.96		LDB3_MOUSE (3-429): 1.27e-25: 113: 27.27
+	Mm
		554938 KPCE_MOUSE (5-662): 0: 624: 45.02		Q9CRA2_MOUSE (238-306): 3.04e-35: 134: 94.20
+	Mm
		554947 KPCE_MOUSE (5-662): 0: 624: 45.02		LDB3_MOUSE (3-429): 1.27e-25: 113: 27.27
+	Mm
		250816 KPCE_MOUSE (5-662): 0: 624: 45.02		FHL2_MOUSE (442-587): 7.03e-16: 80.1: 26.35
+	Mm
		661014 KPCD_MOUSE (6-194): 5.27e-54: 198: 35.20		LDB3_MOUSE (3-429): 1.27e-25: 113: 27.27
+	Mm
		973818 KPCZ_MOUSE (10-86): 5.5e-12: 70.9: 36.36		LIMD1_MOUSE (84-591): 6.22e-64: 224: 15.65
+	Hs
		983894 KPCZ_HUMAN (10-86): 4.47e-12: 71.2: 36.36		AJUBA_HUMAN (79-593): 6.42e-48: 177: 15.28
+	Mm
		973816 KPCZ_MOUSE (10-86): 5.5e-12: 70.9: 36.36		LDB3_MOUSE (3-429): 1.27e-25: 113: 27.27