HitPredict

Interactor 1: KPCB (P05771)
Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)
Gene: PRKCB

Interactor 2: H2B1N (Q99877)
Histone H2B type 1-N (Histone H2B.d) (H2B/d)
Gene: H2BC15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 671 Hs			1 126
+	Hs
		408666 KPCB_HUMAN (1-671): 0: 774: 100.00		H2B1M_HUMAN (1-126): 2.16e-54: 168: 96.83
+	Hs
		408525 KPCB_HUMAN (1-671): 0: 774: 100.00		H2B1J_HUMAN (1-126): 3.1e-54: 167: 97.62
+	Hs
		408583 KPCB_HUMAN (1-671): 0: 774: 100.00		H2BFS_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		408591 KPCB_HUMAN (1-671): 0: 774: 100.00		H2B1C_HUMAN (1-126): 4.4e-54: 167: 99.21
+	Hs
		408624 KPCB_HUMAN (1-671): 0: 774: 100.00		H2B2E_HUMAN (1-126): 2.63e-54: 167: 98.41
+	Hs
		241418 KPCB_HUMAN (1-671): 0: 774: 100.00		H2B1K_HUMAN (1-126): 5.35e-54: 166: 98.41
+	Hs
		408565 KPCB_HUMAN (1-671): 0: 774: 100.00		H2B1B_HUMAN (1-126): 5.35e-54: 166: 98.41
+	Hs
		408585 KPCB_HUMAN (1-671): 0: 774: 100.00		H2B1D_HUMAN (1-126): 1.03e-53: 166: 99.21
+	Hs
		408667 KPCB_HUMAN (1-671): 0: 774: 100.00		H2B1L_HUMAN (1-126): 1.02e-52: 163: 97.62
+	Mm
		682111 AKT1_MOUSE (239-665): 1.05e-159: 470: 37.33		H2B2B_MOUSE (1-126): 1.15e-54: 168: 97.62
+	Hs
		617926 AKT1_HUMAN (239-665): 2.36e-159: 469: 37.33		H2B1O_HUMAN (1-126): 1.42e-54: 168: 97.62
+	Hs
		617927 AKT2_HUMAN (237-665): 2.34e-159: 469: 37.87		H2B1O_HUMAN (1-126): 1.42e-54: 168: 97.62
+	Mm
		682113 AKT1_MOUSE (239-665): 1.05e-159: 470: 37.33		H2B1C_MOUSE (1-126): 4.4e-54: 167: 99.21
+	Hs
		420806 AKT1_HUMAN (239-665): 2.36e-159: 469: 37.33		H2B1J_HUMAN (1-126): 3.1e-54: 167: 97.62
+	Hs
		420807 AKT2_HUMAN (237-665): 2.34e-159: 469: 37.87		H2B1J_HUMAN (1-126): 3.1e-54: 167: 97.62
+	Hs
		681878 AKT1_HUMAN (239-665): 2.36e-159: 469: 37.33		H2B2E_HUMAN (1-126): 2.63e-54: 167: 98.41
+	Hs
		682181 AKT2_HUMAN (237-665): 2.34e-159: 469: 37.87		H2B2E_HUMAN (1-126): 2.63e-54: 167: 98.41
+	Hs
		681686 AKT1_HUMAN (239-665): 2.36e-159: 469: 37.33		H2B1B_HUMAN (1-126): 5.35e-54: 166: 98.41
+	Hs
		682137 AKT2_HUMAN (237-665): 2.34e-159: 469: 37.87		H2B1B_HUMAN (1-126): 5.35e-54: 166: 98.41
+	Hs
		682194 AKT2_HUMAN (237-665): 2.34e-159: 469: 37.87		H2B3B_HUMAN (1-126): 6.57e-52: 161: 96.03