HitPredict

Interactor 1: K1C18 (P05783)
Keratin, type I cytoskeletal 18 (Cell proliferation-inducing gene 46 protein) (Cytokeratin-18) (CK-18) (Keratin-18) (K18)
Gene: KRT18

Interactor 2: VCAM1 (P19320)
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]
Gene: VCAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	19738201, 22623428
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 430 Hs			1 739
+	Hs
		444311 K1C19_HUMAN (79-389): 5.66e-89: 277: 50.64		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		445003 K1C16_HUMAN (77-404): 2.34e-87: 275: 49.85		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		359464 K2C6A_HUMAN (45-406): 1.72e-71: 236: 23.90		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		980246 K1C17_HUMAN (58-420): 5.11e-86: 270: 48.08		CNTN1_HUMAN (5-586): 2.19e-32: 137: 10.44
+	Hs
		408789 K1C18_HUMAN (1-430): 1.32e-72: 236: 100.00		CNTN1_HUMAN (5-586): 2.19e-32: 137: 10.44
+	Hs
		234500 KRT83_HUMAN (12-407): 1e-92: 290: 24.62		DSCAM_HUMAN (10-207): 2.99e-15: 82.3: 12.87