Interactor 1: K1C18 (P05783)
Keratin, type I cytoskeletal 18 (Cell proliferation-inducing gene 46 protein) (Cytokeratin-18) (CK-18) (Keratin-18) (K18)
Gene: KRT18

Interactor 2: K2C6C (P48668)
Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK-6C) (Cytokeratin-6E) (CK-6E) (Keratin K6h) (Keratin-6C) (K6C) (Type-II keratin Kb12)
Gene: KRT6C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.890

The method score is based on:

Property Details
Experiments 32296183, 30021884, 37071682, unassigned1304
Identification Methods two hybrid, proximity labelling technology, cross-linking study, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament
Common GO terms GO:0005829 - cytosol
GO:0005882 - intermediate filament
GO:0045095 - keratin filament
GO:0045104 - intermediate filament cytoskeleton organization
GO:0070062 - extracellular exosome
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 430
Hs

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Last updated: 15 Jul 2024