HitPredict

Interactor 1: K2C8 (P05787)
Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)
Gene: KRT8

Interactor 2: LRC49 (Q8IUZ0)
Leucine-rich repeat-containing protein 49 (Centriolar satellite-associated tubulin polyglutamylase complex regulator 2) (Tubulin polyglutamylase complex subunit 4) (PGs4)
Gene: LRRC49

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 483 Hs			1 686
+	Hs
		232770 K2C7_HUMAN (1-464): 4.13e-154: 448: 60.34		PHLP1_HUMAN (2-482): 2.72e-46: 179: 11.34
+	Hs
		318878 K2C75_HUMAN (2-405): 3.9e-79: 258: 64.04		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		1140447 K2C79_HUMAN (8-415): 2.02e-76: 250: 57.39		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		232764 K2C8_HUMAN (1-483): 2.44e-63: 215: 100.00		PHLP1_HUMAN (2-482): 2.72e-46: 179: 11.34
+	Hs
		531624 K2C5_HUMAN (56-405): 9.54e-66: 223: 71.02		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		359530 K2C6A_HUMAN (56-405): 8.09e-65: 220: 70.74		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		409152 K2C8_HUMAN (1-483): 2.44e-63: 215: 100.00		CEP97_HUMAN (24-184): 1.03e-10: 67: 16.13