HitPredict

Interactor 1: KAPC (P05986)
cAMP-dependent protein kinase type 3 (PKA 3) (EC 2.7.11.11)
Gene: TPK3

Interactor 2: JJJ1 (P53863)
J protein JJJ1
Gene: JJJ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.799

Property	Details
Experiments	11805837, 16319894
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	DnaJ~Pkinase
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 398 Sc			1 590
+	Sc
		412827 KAPA_YEAST (5-398): 3.89e-154: 442: 73.86		JJJ1_YEAST (1-590): 7e-97: 309: 100.00
+	Hs
		609685 KAPCG_HUMAN (77-398): 8.29e-148: 424: 46.27		DNJA3_HUMAN (2-184): 2.16e-47: 174: 21.86
+	Hs
		257909 KAPCA_HUMAN (77-398): 3.73e-149: 428: 48.76		DNJB6_HUMAN (3-105): 1.46e-38: 146: 41.75
+	Hs
		257926 AKT1_HUMAN (59-392): 5.9e-147: 427: 36.10		DNJB6_HUMAN (3-105): 1.46e-38: 146: 41.75
+	Hs
		257912 KAPCG_HUMAN (77-398): 8.29e-148: 424: 46.27		DNJB6_HUMAN (3-105): 1.46e-38: 146: 41.75
+	Sc
		412669 KAPA_YEAST (5-398): 3.89e-154: 442: 73.86		MAS5_YEAST (2-75): 4.21e-15: 79.3: 55.41
+	Hs
		568560 KAPCA_HUMAN (77-398): 3.73e-149: 428: 48.76		DNJA1_HUMAN (2-76): 2.26e-13: 73.9: 53.33
+	Hs
		681410 KPCE_HUMAN (3-398): 2.66e-143: 426: 30.90		DNJA1_HUMAN (2-76): 2.26e-13: 73.9: 53.33
+	Hs
		609648 KAPCG_HUMAN (77-398): 8.29e-148: 424: 46.27		DNJA1_HUMAN (2-76): 2.26e-13: 73.9: 53.33
+	Hs
		681639 KS6B2_HUMAN (74-398): 2.5e-141: 412: 38.39		DNJA1_HUMAN (2-76): 2.26e-13: 73.9: 53.33
+	Sc
		520620 YPK1_YEAST (74-381): 2.19e-81: 264: 44.23		JJJ2_YEAST (2-534): 7.04e-47: 175: 11.26
+	Hs
		217853 PRKY_HUMAN (83-303): 8.55e-84: 258: 50.68		DNJB5_HUMAN (1-260): 1.79e-45: 166: 19.01
+	Sc
		520583 YPK1_YEAST (74-381): 2.19e-81: 264: 44.23		MAS5_YEAST (2-75): 4.21e-15: 79.3: 55.41
+	Hs
		217931 PRKY_HUMAN (83-303): 8.55e-84: 258: 50.68		DNJC2_HUMAN (3-361): 4.41e-10: 64.3: 14.25