HitPredict

Interactor 1: OPS1 (P06002)
Opsin Rh1 (Neither inactivation nor afterpotential E protein) (Outer R1-R6 photoreceptor cells opsin)
Gene: ninaE

Interactor 2: ARRB (P19107)
Phosrestin-1 (49 kDa arrestin-like protein) (Arrestin-2) (Arrestin-B) (Phosrestin I)
Gene: Arr2

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	19720874, 22855823
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~Arrestin_C, 7tm_1~Arrestin_N
Common GO terms	GO:0007601 - visual perception GO:0016028 - rhabdomere GO:0016029 - subrhabdomeral cisterna
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 373 Dm			1 401
+	Hs
		428933 ADRB2_HUMAN (15-361): 6.72e-74: 236: 17.73		ARRB2_HUMAN (5-401): 0: 597: 42.54
+	Rn
		663954 Q8VBU7_RAT (31-366): 3.74e-75: 240: 18.00		ARRB2_RAT (5-401): 0: 591: 41.94
+	Hs
		435863 OPSD_HUMAN (8-369): 1.55e-71: 228: 25.14		ARRB2_HUMAN (5-401): 0: 597: 42.54
+	Hs
		441649 ADRB1_HUMAN (2-365): 1.18e-69: 227: 17.82		ARRB1_HUMAN (5-400): 0: 598: 42.47
+	Hs
		441648 ADRB1_HUMAN (2-365): 1.18e-69: 227: 17.82		ARRB2_HUMAN (5-401): 0: 597: 42.54
+	Hs
		781016 OPRD_HUMAN (1-371): 4.57e-65: 212: 16.14		ARRB1_HUMAN (5-400): 0: 598: 42.47
+	Hs
		208444 OX1R_HUMAN (1-370): 6.96e-64: 211: 19.01		ARRB1_HUMAN (5-400): 0: 598: 42.47
+	Hs
		685822 OPRD_HUMAN (1-371): 4.57e-65: 212: 16.14		ARRB2_HUMAN (5-401): 0: 597: 42.54
+	Hs
		208441 OX1R_HUMAN (1-370): 6.96e-64: 211: 19.01		ARRB2_HUMAN (5-401): 0: 597: 42.54
+	Hs
		685813 APJ_HUMAN (43-372): 6.57e-64: 210: 15.56		ARRB2_HUMAN (5-401): 0: 597: 42.54
+	Dm
		409740 OPS1_DROME (1-373): 6.75e-83: 258: 100.00		ARRA_DROME (1-360): 0: 509: 45.58
+	Hs
		435859 OPSD_HUMAN (8-369): 1.55e-71: 228: 25.14		ARRS_HUMAN (7-401): 0: 519: 39.60
+	Bt
		362126 OPSD_BOVIN (8-369): 2.55e-66: 215: 24.86		ARRS_BOVIN (7-399): 0: 529: 39.55
+	Hs
		435866 OPSD_HUMAN (8-369): 1.55e-71: 228: 25.14		ARRC_HUMAN (6-364): 1.56e-178: 504: 37.13
+	Hs
		656989 5HT2A_HUMAN (49-346): 1.39e-13: 73.6: 26.63		ARRB2_HUMAN (5-401): 0: 597: 42.54