HitPredict

Interactor 1: NOT2 (P06100)
General negative regulator of transcription subunit 2 (cell division cycle protein 36)
Gene: CDC36

Interactor 2: NOT5 (Q12514)
General negative regulator of transcription subunit 5
Gene: NOT5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 10490603, 24121231, 9463387, 11805826, 16429126, 19707589, 37968396, 25914052
Identification Methods coimmunoprecipitation, pull down, tandem affinity purification, affinity chromatography technology
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains NOT2_3_5~NOT2_3_5
Common GO terms GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 - P-body
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 6 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 191
Sc

1 560
+ Sc
+ Hs
+ Dm
+ Sc
+ Mm
+ Ce
+ Ce
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024