HitPredict

Interactor 1: EIF3B (P06103)
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Cell cycle regulation and translation initiation protein) (Eukaryotic translation initiation factor 3 90 kDa subunit) (eIF3 p90) (Translation initiation factor eIF3 p90 subunit)
Gene: PRT1

Interactor 2: IF2B (P09064)
Eukaryotic translation initiation factor 2 subunit beta (eIF2-beta)
Gene: SUI3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	21745818, 11018020, 21280672, 14759368
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001732 - formation of cytoplasmic translation initiation complex GO:0003743 - translation initiation factor activity GO:0006413 - translational initiation GO:0016282 - eukaryotic 43S preinitiation complex GO:0031369 - translation initiation factor binding and 1 others more... GO:0043614 - multi-eIF complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 763 Sc			1 285
+	Hs
		588868 EIF3B_HUMAN (39-762): 0: 794: 29.17		IF2B_HUMAN (54-285): 8.54e-86: 261: 45.57
+	Sc
		410115 EIF3B_YEAST (1-763): 0: 875: 100.00		IF5_YEAST (139-268): 6.52e-43: 153: 26.67
+	Hs
		873793 EIF3B_HUMAN (39-762): 0: 794: 29.17		IF5_HUMAN (146-265): 1.51e-46: 163: 24.00