HitPredict

Interactor 1: UBC2 (P06104)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Radiation sensitivity protein 6) (Ubiquitin carrier protein UBC2) (Ubiquitin-protein ligase UBC2)
Gene: RAD6

Interactor 2: UBI4P (P0CG63)
Polyubiquitin [Cleaved into: Ubiquitin]
Gene: UBI4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	2065660, 36912886
Identification Methods	pull down, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 172 Sc			1 381
+	Sc
		477103 UBC4_YEAST (1-149): 1.43e-79: 234: 38.26		UBI4P_YEAST (1-381): 4.37e-161: 458: 100.00
+	Rn
		88580 UB2D1_RAT (4-150): 6.66e-81: 237: 37.42		UBC_RAT (1-333): 8.71e-131: 395: 93.99
+	Mm
		476737 UB2D3_MOUSE (4-150): 1.63e-79: 234: 38.10		UBC_MOUSE (1-333): 9.24e-132: 396: 93.99
+	At
		1091932 UBC28_ARATH (4-150): 1.3e-81: 239: 38.10		UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05
+	At
		715116 UBC8_ARATH (4-150): 3.98e-81: 238: 37.42		UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05
+	At
		715132 UBC9_ARATH (4-150): 1.85e-80: 236: 38.10		UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05
+	At
		715147 UBC10_ARATH (4-150): 1.69e-80: 236: 37.42		UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05
+	At
		715157 UBC11_ARATH (4-150): 2.2e-80: 236: 36.74		UBQ3_ARATH (77-381): 2.59e-125: 365: 97.05
+	Xl
		919927 UB2D2_XENLA (4-150): 7.04e-81: 237: 38.10		Q7SY79_XENLA (1-229): 7.03e-88: 279: 95.63
+	Dm
		639414 UBCD1_DROME (4-150): 2.89e-80: 236: 38.10		Q9W418_DROME (1-230): 6.72e-89: 279: 95.22
+	Hs
		475249 UB2D4_HUMAN (4-150): 1.33e-81: 239: 38.78		UBB_HUMAN (77-304): 5.9e-91: 274: 96.05
+	Hs
		474984 UB2D2_HUMAN (4-150): 7.04e-81: 237: 38.10		UBB_HUMAN (77-304): 5.9e-91: 274: 96.05
+	Hs
		476604 UB2D4_HUMAN (4-150): 1.33e-81: 239: 38.78		UBC_HUMAN (1-153): 1.84e-50: 181: 95.43
+	Hs
		475501 UB2D1_HUMAN (4-150): 6.66e-81: 237: 37.42		UBC_HUMAN (1-153): 1.84e-50: 181: 95.43
+	Hs
		475586 UB2D2_HUMAN (4-150): 7.04e-81: 237: 38.10		UBC_HUMAN (1-153): 1.84e-50: 181: 95.43
+	Hs
		475550 UB2D3_HUMAN (4-150): 1.63e-79: 234: 38.10		UBC_HUMAN (1-153): 1.84e-50: 181: 95.43
+	Hs
		476218 UB2E2_HUMAN (3-150): 5.11e-74: 222: 33.11		UBC_HUMAN (1-153): 1.84e-50: 181: 95.43
+	Hs
		171490 UB2D2_HUMAN (4-150): 7.04e-81: 237: 38.10		UBD_HUMAN (231-380): 1.48e-30: 116: 30.77
+	Hs
		397879 UB2D3_HUMAN (4-150): 1.63e-79: 234: 38.10		ISG15_HUMAN (3-152): 9.45e-31: 117: 32.68
+	Hs
		895773 UB2D3_HUMAN (4-150): 1.63e-79: 234: 38.10		RS27A_HUMAN (77-153): 8.44e-20: 87: 94.81