HitPredict

Interactor 1: UBC2 (P06104)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Radiation sensitivity protein 6) (Ubiquitin carrier protein UBC2) (Ubiquitin-protein ligase UBC2)
Gene: RAD6

Interactor 2: RAD18 (P10862)
Postreplication repair E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAD18) (Radiation sensitivity protein 18)
Gene: RAD18

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 9287349, 10688190, 9234711, 10880451, 23034805, 16611731, 16957771, 18385374, 16554755, 32228444, 16344468, 7926769, 19851286, 24224485, 11805837, 12535539, 33570581, 18485869, 37968396, 36162503 and 1 others

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Identification Methods biochemical, two hybrid, filter binding, coimmunoprecipitation, affinity chromatography technology, pull down, far western blotting, enzymatic study, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-C3HC4_2
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0032508 - DNA duplex unwinding
GO:0042275 - error-free postreplication DNA repair
GO:0042276 - error-prone translesion synthesis
and 2 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 172
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024