HitPredict

Interactor 1: UBC2 (P06104)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Radiation sensitivity protein 6) (Ubiquitin carrier protein UBC2) (Ubiquitin-protein ligase UBC2)
Gene: RAD6

Interactor 2: UBA4 (P38820)
Adenylyltransferase and sulfurtransferase UBA4 (Needs CLA4 to survive protein 3) (Ubiquitin-like protein activator 4) [Includes: Adenylyltransferase UBA4 (EC 2.7.7.-); Sulfurtransferase UBA4 (EC 2.8.1.-)]
Gene: UBA4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9287349
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ThiF~UQ_con
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 172 Sc			1 440
+	Hs
		919856 UB2D2_HUMAN (4-150): 7.04e-81: 237: 38.10		UBA5_HUMAN (4-275): 9.09e-65: 215: 20.67
+	Hs
		919796 UB2D2_HUMAN (4-150): 7.04e-81: 237: 38.10		UBA3_HUMAN (1-230): 6.63e-62: 209: 23.58
+	Sp
		293848 UBC4_SCHPO (4-149): 3.97e-79: 233: 40.41		UBA1_SCHPO (43-358): 2.11e-57: 205: 15.17
+	Hs
		1282360 UB2E3_HUMAN (3-150): 6.01e-74: 222: 33.11		SAE2_HUMAN (51-226): 3.88e-57: 200: 25.42
+	Sp
		293847 UBC2_SCHPO (1-150): 1.03e-70: 211: 77.33		UBA1_SCHPO (43-358): 2.11e-57: 205: 15.17
+	Hs
		607190 UB2D4_HUMAN (4-150): 1.33e-81: 239: 38.78		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607026 UB2D1_HUMAN (4-150): 6.66e-81: 237: 37.42		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607050 UB2D2_HUMAN (4-150): 7.04e-81: 237: 38.10		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607039 UB2D3_HUMAN (4-150): 1.63e-79: 234: 38.10		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Sc
		549788 UBC4_YEAST (1-149): 1.43e-79: 234: 38.26		UBA1_YEAST (33-418): 9.78e-41: 157: 15.29
+	Sc
		410211 UBC2_YEAST (1-150): 1.23e-78: 232: 100.00		UBA1_YEAST (33-418): 9.78e-41: 157: 15.29
+	Hs
		607129 UB2E3_HUMAN (3-150): 6.01e-74: 222: 33.11		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607136 UB2E2_HUMAN (3-150): 5.11e-74: 222: 33.11		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607023 UBE2A_HUMAN (1-151): 9.07e-74: 220: 69.54		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607028 UB2E1_HUMAN (3-150): 4.36e-73: 219: 33.78		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607054 UBE2B_HUMAN (1-151): 7.03e-73: 217: 69.54		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607038 UB2G2_HUMAN (1-148): 8.75e-34: 119: 37.65		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Sc
		608719 UBC7_YEAST (1-148): 7.26e-37: 126: 37.65		UBA1_YEAST (33-418): 9.78e-41: 157: 15.29
+	Hs
		782203 UB2E1_HUMAN (3-150): 4.36e-73: 219: 33.78		UBA7_HUMAN (46-200): 2.1e-09: 62: 32.93