HitPredict

Interactor 1: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: QSOX2 (Q6ZRP7)
Sulfhydryl oxidase 2 (EC 1.8.3.2) (Neuroblastoma-derived sulfhydryl oxidase) (Quiescin Q6-like protein 1)
Gene: QSOX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1382 Hs			1 698
+	Hs
		435677 IGF1R_HUMAN (31-1380): 0: 1353: 56.11		QSOX2_HUMAN (10-698): 0: 680: 100.00
+	Rn
		514117 INSR_RAT (1-1382): 0: 1527: 94.44		PDIA3_RAT (38-570): 5.53e-107: 336: 12.13
+	Hs
		411391 INSR_HUMAN (1-1382): 0: 1530: 100.00		PDIA6_HUMAN (36-423): 6.73e-65: 223: 14.62
+	Rn
		544870 INSR_RAT (1-1382): 0: 1527: 94.44		PDIA6_RAT (36-423): 5.31e-65: 223: 15.08
+	Hs
		411285 INSR_HUMAN (1-1382): 0: 1530: 100.00		PDIA4_HUMAN (63-393): 2.86e-41: 162: 14.78
+	Hs
		411271 INSR_HUMAN (1-1382): 0: 1530: 100.00		PDIA1_HUMAN (19-174): 7.79e-32: 131: 21.80
+	Rn
		388065 INSR_RAT (1-1382): 0: 1527: 94.44		PDIA1_RAT (19-206): 2.53e-31: 130: 19.58
+	Hs
		411430 INSR_HUMAN (1-1382): 0: 1530: 100.00		DJC10_HUMAN (57-290): 5.36e-28: 122: 14.96
+	Hs
		411442 INSR_HUMAN (1-1382): 0: 1530: 100.00		TXND5_HUMAN (28-180): 6.57e-29: 122: 20.61
+	Rn
		102493 INSR_RAT (1-1382): 0: 1527: 94.44		G3V6T7_RAT (448-556): 4.91e-09: 61.5: 11.71
+	Hs
		435520 IGF1R_HUMAN (31-1380): 0: 1353: 56.11		PDIA4_HUMAN (63-393): 2.86e-41: 162: 14.78
+	Hs
		423108 IGF1R_HUMAN (31-1380): 0: 1353: 56.11		PDIA1_HUMAN (19-174): 7.79e-32: 131: 21.80
+	Hs
		435692 IGF1R_HUMAN (31-1380): 0: 1353: 56.11		DJC10_HUMAN (57-290): 5.36e-28: 122: 14.96
+	Hs
		537757 INSRR_HUMAN (13-1341): 0: 1293: 51.12		DJC10_HUMAN (57-290): 5.36e-28: 122: 14.96
+	Hs
		537760 INSRR_HUMAN (13-1341): 0: 1293: 51.12		TXND5_HUMAN (28-180): 6.57e-29: 122: 20.61
+	Hs
		531732 EPHB2_HUMAN (521-1316): 3.12e-175: 551: 20.21		PDIA4_HUMAN (63-393): 2.86e-41: 162: 14.78
+	Hs
		531731 EPHA8_HUMAN (644-1322): 3.66e-168: 531: 20.68		PDIA4_HUMAN (63-393): 2.86e-41: 162: 14.78
+	Hs
		445818 ROS1_HUMAN (511-1377): 3.38e-158: 530: 22.63		PDIA4_HUMAN (63-393): 2.86e-41: 162: 14.78
+	Hs
		445858 ROS1_HUMAN (511-1377): 3.38e-158: 530: 22.63		DJC10_HUMAN (57-290): 5.36e-28: 122: 14.96
+	Hs
		383571 ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67		PDIA4_HUMAN (63-393): 2.86e-41: 162: 14.78