HitPredict

Interactor 1: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: TTC13 (Q8NBP0)
Tetratricopeptide repeat protein 13 (TPR repeat protein 13)
Gene: TTC13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1382 Hs			1 860
+	Hs
		435695 IGF1R_HUMAN (31-1380): 0: 1353: 56.11		TTC13_HUMAN (1-860): 0: 717: 100.00
+	Rn
		193482 INSR_RAT (1-1382): 0: 1527: 94.44		STIP1_RAT (140-570): 6.88e-22: 102: 13.23
+	Hs
		411373 INSR_HUMAN (1-1382): 0: 1530: 100.00		DNJC3_HUMAN (24-462): 8.46e-18: 89.5: 13.51
+	Hs
		435627 IGF1R_HUMAN (31-1380): 0: 1353: 56.11		DNJC3_HUMAN (24-462): 8.46e-18: 89.5: 13.51
+	Hs
		1028051 EPHA7_HUMAN (562-1356): 4.76e-172: 541: 19.48		DNJC3_HUMAN (24-462): 8.46e-18: 89.5: 13.51
+	Hs
		445848 ROS1_HUMAN (511-1377): 3.38e-158: 530: 22.63		DNJC3_HUMAN (24-462): 8.46e-18: 89.5: 13.51
+	Hs
		384341 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		CDC27_HUMAN (14-504): 1.98e-52: 198: 13.57
+	Hs
		383642 ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67		STIP1_HUMAN (140-570): 6.24e-22: 102: 13.02
+	Hs
		383952 ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67		Q9BPW0_HUMAN (56-203): 1.72e-12: 72.7: 13.42
+	Hs
		385407 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		DNJC7_HUMAN (244-548): 6.47e-29: 123: 14.33
+	Hs
		1028125 ALK_HUMAN (982-1339): 1.96e-70: 263: 40.53		DNJC3_HUMAN (24-462): 8.46e-18: 89.5: 13.51
+	Hs
		384359 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		STIP1_HUMAN (140-570): 6.24e-22: 102: 13.02
+	Hs
		174540 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		OGT1_HUMAN (350-680): 8.03e-19: 94.2: 14.00
+	Hs
		385317 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		TTC28_HUMAN (257-732): 2.35e-17: 89.6: 11.91
+	Hs
		385023 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		SKI3_HUMAN (28-624): 1.38e-16: 86.9: 11.52
+	Hs
		385527 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		RPAP3_HUMAN (88-330): 7.28e-16: 84: 19.62
+	Hs
		1028052 NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43		DNJC3_HUMAN (24-462): 8.46e-18: 89.5: 13.51
+	Hs
		385022 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		CTR9_HUMAN (231-485): 1.61e-12: 73.7: 10.43
+	Hs
		384545 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		PPP5_HUMAN (56-203): 2.44e-12: 72.3: 13.42
+	Dm
		526801 7LESS_DROME (1017-1290): 6.19e-65: 246: 45.23		Q9VH81_DROME (32-279): 1.21e-11: 70: 10.08