HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000242 - pericentriolar material GO:0005524 - ATP binding GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 509 Hs			1 556
+	Hs
		411642 LCK_HUMAN (1-509): 0: 661: 100.00		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		411833 LCK_HUMAN (1-509): 0: 661: 100.00		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		411996 FYN_HUMAN (30-507): 0: 586: 59.01		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		411639 LCK_HUMAN (1-509): 0: 661: 100.00		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Hs
		433248 YES_HUMAN (26-507): 0: 581: 58.06		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		454796 FGR_HUMAN (1-507): 0: 579: 52.76		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		412086 FYN_HUMAN (30-507): 0: 586: 59.01		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		433290 YES_HUMAN (26-507): 0: 581: 58.06		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		454809 FGR_HUMAN (1-507): 0: 579: 52.76		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		412325 FYN_HUMAN (30-507): 0: 586: 59.01		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		826575 BLK_HUMAN (1-509): 0: 557: 59.35		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		454845 FGR_HUMAN (1-507): 0: 579: 52.76		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		412084 FYN_HUMAN (30-507): 0: 586: 59.01		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Hs
		454808 FGR_HUMAN (1-507): 0: 579: 52.76		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Hs
		846519 BLK_HUMAN (1-509): 0: 557: 59.35		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		826630 ITK_HUMAN (7-500): 1.08e-177: 515: 33.33		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		821128 BLK_HUMAN (1-509): 0: 557: 59.35		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Hs
		573257 PTK6_HUMAN (63-499): 1.36e-161: 467: 40.41		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		826655 PTK6_HUMAN (63-499): 1.36e-161: 467: 40.41		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		821206 PTK6_HUMAN (63-499): 1.36e-161: 467: 40.41		TCPE_HUMAN (4-530): 0: 550: 31.96