HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: BCL3 (P20749)
B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3)
Gene: BCL3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.690

Property	Details
Experiments	16099425
Identification Methods	pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 454
+	Hs
		411877 LCK_HUMAN (1-509): 0: 661: 100.00		RAI14_HUMAN (120-426): 2.96e-81: 271: 27.76
+	Hs
		412002 FYN_HUMAN (30-507): 0: 586: 59.01		BCL3_HUMAN (1-454): 1.07e-97: 302: 100.00
+	Hs
		411885 LCK_HUMAN (1-509): 0: 661: 100.00		KDIS_HUMAN (213-454): 2.8e-56: 203: 18.60
+	Hs
		434045 LYN_HUMAN (1-509): 0: 582: 62.72		RAI14_HUMAN (120-426): 2.96e-81: 271: 27.76
+	Hs
		434071 LYN_HUMAN (1-509): 0: 582: 62.72		KDIS_HUMAN (213-454): 2.8e-56: 203: 18.60
+	Hs
		433701 LYN_HUMAN (1-509): 0: 582: 62.72		ANK2_HUMAN (211-454): 7.66e-48: 179: 20.31
+	Hs
		411697 LCK_HUMAN (1-509): 0: 661: 100.00		ANK3_HUMAN (6-154): 9.65e-19: 91.6: 17.33
+	Hs
		337406 ABL1_HUMAN (49-502): 8.1e-171: 513: 42.21		DAPK1_HUMAN (165-452): 5.01e-59: 211: 18.97
+	Hs
		522789 SRC_HUMAN (20-507): 0: 586: 55.00		IKBA_HUMAN (133-319): 1.34e-24: 105: 37.57
+	Hs
		433258 YES_HUMAN (26-507): 0: 581: 58.06		IKBA_HUMAN (133-319): 1.34e-24: 105: 37.57
+	Hs
		434072 LYN_HUMAN (1-509): 0: 582: 62.72		ANR50_HUMAN (323-454): 3.77e-19: 92.8: 14.39
+	Hs
		433730 LYN_HUMAN (1-509): 0: 582: 62.72		ANK3_HUMAN (6-154): 9.65e-19: 91.6: 17.33
+	Hs
		337352 ABL1_HUMAN (49-502): 8.1e-171: 513: 42.21		IKBA_HUMAN (133-319): 1.34e-24: 105: 37.57
+	Dm
		337696 SRC64_DROME (39-507): 7.74e-179: 515: 46.33		TNKS_DROME (132-354): 4.48e-13: 73.6: 29.58