HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SAM_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 1202
+	Hs
		433738 LYN_HUMAN (1-509): 0: 582: 62.72		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		411780 LCK_HUMAN (1-509): 0: 661: 100.00		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		412287 FYN_HUMAN (30-507): 0: 586: 59.01		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		412058 FYN_HUMAN (30-507): 0: 586: 59.01		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		433620 LYN_HUMAN (1-509): 0: 582: 62.72		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		111443 J3QRU1_HUMAN (26-507): 0: 581: 58.06		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		433272 YES_HUMAN (26-507): 0: 581: 58.06		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		724720 BLK_HUMAN (1-509): 0: 557: 59.35		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		523231 SRC_HUMAN (20-507): 0: 586: 55.00		MYH4_HUMAN (461-886): 4.97e-11: 69.7: 7.67
+	Hs
		433866 LYN_HUMAN (1-509): 0: 582: 62.72		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62