HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: AJUBA (Q96IF1)
LIM domain-containing protein ajuba
Gene: AJUBA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	15870274
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 509 Hs			1 538
+	Hs
		442837 HCK_HUMAN (1-509): 0: 602: 65.04		TRIP6_HUMAN (80-530): 6.56e-57: 199: 25.81
+	Hs
		411641 LCK_HUMAN (1-509): 0: 661: 100.00		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Hs
		523001 SRC_HUMAN (20-507): 0: 586: 55.00		TRIP6_HUMAN (80-530): 6.56e-57: 199: 25.81
+	Hs
		442827 HCK_HUMAN (1-509): 0: 602: 65.04		FHL2_HUMAN (364-537): 2.12e-34: 132: 22.16
+	Hs
		442793 HCK_HUMAN (1-509): 0: 602: 65.04		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Mm
		403454 SRC_MOUSE (28-507): 0: 583: 57.05		PAXI_MOUSE (19-459): 2.03e-31: 130: 18.50
+	Hs
		412085 FYN_HUMAN (30-507): 0: 586: 59.01		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Hs
		522857 SRC_HUMAN (20-507): 0: 586: 55.00		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Hs
		433646 LYN_HUMAN (1-509): 0: 582: 62.72		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Hs
		433288 YES_HUMAN (26-507): 0: 581: 58.06		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Hs
		254384 SRC_HUMAN (20-507): 0: 586: 55.00		LDB3_HUMAN (16-537): 2.83e-26: 115: 13.50
+	Hs
		823358 BLK_HUMAN (1-509): 0: 557: 59.35		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Hs
		111447 J3QRU1_HUMAN (26-507): 0: 581: 58.06		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Hs
		433484 YES_HUMAN (26-507): 0: 581: 58.06		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Mm
		337635 ABL1_MOUSE (49-502): 5.34e-171: 513: 42.21		PAXI_MOUSE (19-459): 2.03e-31: 130: 18.50
+	Hs
		337395 ABL1_HUMAN (49-502): 8.1e-171: 513: 42.21		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Ce
		107567 SRC2_CAEEL (35-507): 0: 526: 47.71		G5EFG1_CAEEL (16-454): 1.46e-24: 110: 15.15
+	Hs
		789046 ABL2_HUMAN (57-502): 3.29e-166: 502: 42.95		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Ce
		106629 SRC1_CAEEL (1-508): 8.64e-179: 514: 44.84		G5EFG1_CAEEL (16-454): 1.46e-24: 110: 15.15
+	Hs
		788979 TEC_HUMAN (7-503): 2.17e-169: 494: 32.56		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72