HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: TANC1 (Q9C0D5)
Protein TANC1 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1)
Gene: TANC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 1861
+	Hs
		433991 LYN_HUMAN (1-509): 0: 582: 62.72		TANC1_HUMAN (1-1861): 0: 1674: 100.00
+	Hs
		434072 LYN_HUMAN (1-509): 0: 582: 62.72		ANR50_HUMAN (385-1762): 0: 692: 21.25
+	Hs
		411697 LCK_HUMAN (1-509): 0: 661: 100.00		ANK3_HUMAN (758-1857): 3.69e-163: 558: 13.95
+	Hs
		433730 LYN_HUMAN (1-509): 0: 582: 62.72		ANK3_HUMAN (758-1857): 3.69e-163: 558: 13.95
+	Hs
		433701 LYN_HUMAN (1-509): 0: 582: 62.72		ANK2_HUMAN (832-1445): 1.76e-99: 360: 19.88
+	Dm
		337696 SRC64_DROME (39-507): 7.74e-179: 515: 46.33		TNKS_DROME (670-1199): 5.77e-96: 340: 18.45
+	Hs
		411885 LCK_HUMAN (1-509): 0: 661: 100.00		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		434071 LYN_HUMAN (1-509): 0: 582: 62.72		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		337406 ABL1_HUMAN (49-502): 8.1e-171: 513: 42.21		DAPK1_HUMAN (1137-1270): 4.08e-10: 67.4: 32.09