Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 31980649, 7687536, 11157475, 27001024, 14993658
Identification Methods affinity chromatography technology, x-ray crystallography, enzymatic study, protein kinase assay
Interaction Type physical association, association, direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0000304 - response to singlet oxygen
GO:0001764 - neuron migration
GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0002250 - adaptive immune response
GO:0002862 - negative regulation of inflammatory response to antigenic stimulus
and 84 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 537
Hs

1 537
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024