Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: STAT3 (P40763)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 12244095
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2, SH2~SH2, SH2~SH3_1
Common GO terms GO:0005102 - signaling receptor binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0010629 - negative regulation of gene expression
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 537
Hs

1 770
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Last updated: 15 Jul 2024