HitPredict

Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 537 Hs			1 227
+	Hs
		433298 YES_HUMAN (1-537): 0: 591: 71.61		RND2_HUMAN (1-227): 7.71e-110: 316: 100.00
+	Hs
		412115 FYN_HUMAN (1-537): 0: 643: 100.00		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		411948 FYN_HUMAN (1-537): 0: 643: 100.00		RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11
+	Hs
		433308 YES_HUMAN (1-537): 0: 591: 71.61		RND3_HUMAN (4-227): 3.64e-100: 292: 64.00
+	Hs
		412123 FYN_HUMAN (1-537): 0: 643: 100.00		RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25
+	Hs
		411980 FYN_HUMAN (1-537): 0: 643: 100.00		RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43
+	Hs
		433307 YES_HUMAN (1-537): 0: 591: 71.61		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		433217 YES_HUMAN (1-537): 0: 591: 71.61		RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11
+	Hs
		522888 SRC_HUMAN (1-537): 0: 598: 68.21		RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25
+	Hs
		523004 SRC_HUMAN (1-537): 0: 598: 68.21		RB11B_HUMAN (3-224): 2.23e-77: 233: 18.83
+	Hs
		522882 SRC_HUMAN (1-537): 0: 598: 68.21		RB11A_HUMAN (3-224): 7.25e-77: 232: 21.08
+	Hs
		433314 YES_HUMAN (1-537): 0: 591: 71.61		RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25
+	Hs
		412120 FYN_HUMAN (1-537): 0: 643: 100.00		RHOB_HUMAN (7-184): 9.27e-58: 182: 46.63
+	Hs
		433312 YES_HUMAN (1-537): 0: 591: 71.61		RB11A_HUMAN (3-224): 7.25e-77: 232: 21.08
+	Hs
		433304 YES_HUMAN (1-537): 0: 591: 71.61		RAC3_HUMAN (8-182): 2.88e-76: 230: 42.86
+	Hs
		433239 YES_HUMAN (1-537): 0: 591: 71.61		RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43
+	Hs
		412361 FYN_HUMAN (1-537): 0: 643: 100.00		RHOF_HUMAN (9-191): 9.16e-51: 165: 43.01
+	Hs
		522885 SRC_HUMAN (1-537): 0: 598: 68.21		RHOB_HUMAN (7-184): 9.27e-58: 182: 46.63
+	Hs
		433313 YES_HUMAN (1-537): 0: 591: 71.61		RHOB_HUMAN (7-184): 9.27e-58: 182: 46.63
+	Hs
		120279 YES_HUMAN (1-537): 0: 591: 71.61		RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48