HitPredict

Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 537 Hs			1 463
+	Hs
		522880 SRC_HUMAN (1-537): 0: 598: 68.21		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Hs
		442807 HCK_HUMAN (1-535): 0: 548: 56.64		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Hs
		433678 LYN_HUMAN (1-535): 0: 535: 54.48		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Mm
		639439 LYN_MOUSE (1-535): 0: 535: 53.92		HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00
+	Hs
		903901 ITK_HUMAN (4-526): 5.88e-165: 483: 31.90		HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00
+	Mm
		904243 ITK_MOUSE (5-526): 6.73e-164: 480: 32.77		HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00
+	Hs
		522876 SRC_HUMAN (1-537): 0: 598: 68.21		PCBP3_HUMAN (2-114): 1.36e-12: 70.9: 16.24
+	Hs
		522998 SRC_HUMAN (1-537): 0: 598: 68.21		PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21
+	Hs
		434107 LYN_HUMAN (1-535): 0: 535: 54.48		IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00
+	Hs
		433946 LYN_HUMAN (1-535): 0: 535: 54.48		FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41
+	Hs
		789115 FRK_HUMAN (77-529): 6.35e-176: 507: 52.26		PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15