Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: NMDE2 (Q13224)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)
Gene: GRIN2B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.602

The method score is based on:

Property Details
Experiments 10458595, 9670010
Identification Methods pull down, enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0045471 - response to ethanol
GO:1902951 - negative regulation of dendritic spine maintenance
GO:2001056 - positive regulation of cysteine-type endopeptidase activity
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 537
Hs

1 1484
+ Mm
+ Hs
+ Hs
+ Hs
+ Rn
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024