HitPredict

Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.743

The method score is based on:

Property Details
Experiments 17474147, unassigned1973
Identification Methods peptide array, two hybrid fragment pooling approach
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH3_1, PK_Tyr_Ser-Thr~SH3_9, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0005886 - plasma membrane
GO:0030163 - protein catabolic process
GO:0030425 - dendrite
GO:0050852 - T cell receptor signaling pathway
GO:1900182 - positive regulation of protein localization to nucleus
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 537
Hs

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Last updated: 15 Jul 2024