HitPredict

Interactor 1: CDC7 (P06243)
Cell division control protein 7 (EC 2.7.11.1)
Gene: CDC7

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	11805837, 19013276
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 507 Sc			1 405
+	Sc
		412563 CDC7_YEAST (1-507): 1.6e-129: 387: 100.00		PRS4_YEAST (72-395): 3.99e-106: 321: 49.85
+	Hs
		681769 AKT1_HUMAN (3-381): 4.14e-106: 326: 11.17		PRS8_HUMAN (3-405): 1.36e-129: 380: 73.95
+	Sc
		412545 CDC7_YEAST (1-507): 1.6e-129: 387: 100.00		PRS7_YEAST (83-391): 1.16e-104: 318: 51.78
+	Dm
		186169 PDPK1_DROME (31-497): 4.12e-71: 243: 18.24		PRS8_DROME (1-405): 2.81e-131: 384: 73.83
+	Dm
		1376219 PDPK1_DROME (31-497): 4.12e-71: 243: 18.24		Q9W414_DROME (1-402): 3.17e-123: 364: 43.28
+	Sc
		865839 CBK1_YEAST (2-435): 4.64e-62: 218: 16.02		PRS8_YEAST (1-405): 6.47e-132: 386: 100.00
+	Dm
		1359422 PDPK1_DROME (31-497): 4.12e-71: 243: 18.24		Q9V405_DROME (5-397): 1.09e-118: 352: 39.50
+	Dm
		820532 PDPK1_DROME (31-497): 4.12e-71: 243: 18.24		PRS4_DROME (2-395): 3.49e-118: 352: 43.40
+	Hs
		625301 CDK2_HUMAN (31-324): 4.65e-62: 206: 20.59		PRS8_HUMAN (3-405): 1.36e-129: 380: 73.95
+	Hs
		325650 LATS1_HUMAN (16-434): 3.63e-63: 224: 18.25		PRS6B_HUMAN (13-397): 3.38e-118: 351: 41.04
+	Hs
		625315 CDK2_HUMAN (31-324): 4.65e-62: 206: 20.59		PRS10_HUMAN (20-402): 2.79e-124: 366: 43.34
+	Dm
		1181065 PDPK1_DROME (31-497): 4.12e-71: 243: 18.24		Q7KMQ0_DROME (60-390): 1.44e-108: 327: 51.05
+	Dm
		186123 AKT1_DROME (202-440): 1.16e-17: 88.1: 10.88		PRS8_DROME (1-405): 2.81e-131: 384: 73.83
+	Dm
		1213440 AKT1_DROME (202-440): 1.16e-17: 88.1: 10.88		Q9W414_DROME (1-402): 3.17e-123: 364: 43.28
+	Hs
		906937 KS6B2_HUMAN (240-489): 2.44e-15: 80.4: 12.40		PRS4_HUMAN (2-395): 3.16e-121: 360: 44.92
+	Dm
		820489 AKT1_DROME (202-440): 1.16e-17: 88.1: 10.88		PRS4_DROME (2-395): 3.49e-118: 352: 43.40
+	At
		621724 CDKA1_ARATH (276-339): 3.17e-13: 72.2: 32.81		PRS6B_ARATH (1-402): 3.34e-120: 356: 39.55
+	Dm
		1181018 AKT1_DROME (202-440): 1.16e-17: 88.1: 10.88		Q7KMQ0_DROME (60-390): 1.44e-108: 327: 51.05
+	Hs
		730374 KS6B2_HUMAN (240-489): 2.44e-15: 80.4: 12.40		PRS7_HUMAN (60-390): 7.87e-110: 331: 51.05
+	Sc
		339546 CDK1_YEAST (236-339): 3.85e-12: 69.1: 24.04		PRS7_YEAST (83-391): 1.16e-104: 318: 51.78